On January 20, 1922, Assistant Professor Eduard Radošević was appointed as the new Chair of Odontology in the School of Medicine.

In the school's earlier days, there was little space for lectures and no provision for clinical dental courses.

In 1951, the Ministry of Public Health of the People's Republic of Croatia issued the order for the formation of the Odontological Department.

In 1957, the Odontological Section was renamed as the Dentistry Department, and graduate students received the academic title of Doctor of Medicinae Stomatologicae.

Following these events, the Croatian Parliament made the decision in 1962 to create the independent 'School of Dental Medicine at University of Zagreb'.