The newly established private high school for girls, Goryoukan Academy, has a hidden face that people on the outside don't know about.

Some of the things that make Schoolgirl Strikers different from your average card collecting game are the special story missions and the 3D battle system; along with the ability to dress the girls up as you see fit.

An original anime television adaption has been announced, Hiroshi Nishikiori directed the series at J.C.Staff with scripts written by Takao Yoshioka and Mizuto Suzuki and Kengo Tokusashi produced the music at Square Enix.

[6] Schoolgirl Strikers: Twinkle Melodies (スクールガールストライカーズ ～トゥインクルメロディーズ～, Sukurugāru Sutorāikazu ~Tuinkuru Merodīzu~) is a spin-off game also released for iPhone and Android devices.

Characters from the original Schoolgirl Strikers appears in Twinkle Melodies, with the exception of Chocolate Mira and Almond Fomalhaut groups as the Others as well.