[2] Copeland played the 2010 season with the Low–A Aberdeen IronBirds and Single–A Delmarva Shorebirds, and totaled a 3–5 win–loss record, 2.66 earned run average (ERA), and 53 strikeouts in 71 innings pitched.

[1] In the offseason he played for the Estrellas de Oriente of the Dominican Winter League, posting a 2–0 record and a 1.23 ERA in 291⁄3 innings.

Following a Blue Jays loss on May 1, 2015, Copeland was promoted to the major leagues for the first time, replacing Andrew Albers on the roster.

He was recalled by Toronto again on June 2 to be the 26th man for the second game of a doubleheader against the Washington Nationals, and was returned to Buffalo the next day.

[9] He was recalled on June 16, after Sanchez was placed on the disabled list,[10] and made 2 additional starts for the Blue Jays before returning to Buffalo.

[13] Copeland elected free agency on November 6, 2015,[14] but was re-signed to a minor league contract by the Blue Jays on December 18, that included an invitation to spring training.

[16] On April 9, 2016, Copeland's contract was sold to the LG Twins of the KBO League for an undisclosed transfer fee.

[18] After 13 starts, he was waived and released on July 8, and replaced on the Twins' roster by another former major league pitcher, David Huff.

[19] On July 24, 2016, Copeland signed a minor league contract to return the Toronto Blue Jays, and was assigned to the Triple–A Buffalo Bisons.