The team began play in 1993 as a member of the Triple-A American Association (AA) when the Denver Zephyrs relocated to New Orleans.

New Orleans has qualified for the postseason on three occasions and has won the PCL championship twice as the Triple-A affiliate of the Houston Astros (1998 and 2001).

With the arrival of the Colorado Rockies Major League Baseball expansion team, the city's Denver Zephyrs were forced to relocate.

Louisiana lawyer and business promoter Robert E. Couhig, Jr. led the effort to relocate the team to New Orleans.

The Zephyrs were also slated to participate in the 2001 championship series with the Tacoma Rainiers, but the playoffs were cancelled in the wake of the September 11 attacks, and the teams were named co-champions.

The Zephyrs finished out the last portion of their home games for the 2005 Pacific Coast League season three days before Hurricane Katrina hit the City of New Orleans, and though Zephyr Field sustained moderate damage,[6][irrelevant citation] the team was able to open the 2006 season at home, making them the first professional team in New Orleans to do so after the hurricane.

A name-the-team contest was held in search of a new team name to be accompanied by a new color scheme and logos by Brandiose.

[16][17] At the time of the branding announcement, the team noted fan interest in retaining the Zephyrs moniker, but pointed out that the name had relocated from Denver to New Orleans and had no regional ties or significance other than the roller coaster at Pontchartrain Beach which closed in 1983.

[19] On September 2, 2019, the PCL Triple-A New Orleans Baby Cakes played their final game ever as the "Baby Cakes" on the road against the Oklahoma City Dodgers in Oklahoma City with a 10-1 win over the Dodgers to cap off 27 years of Triple-A baseball in the Big Easy since the team relocated there in 1993.