After receiving a lot of attention and being tipped as a future champion in the sport, Quigg had one adult fight at professional rules in Muay Thai scoring a win, before taking the decision to change disciplines and focus his talents towards amateur boxing.
Quigg fought six more times in 2008, winning on each occasion, a run that included a victory over Ghana's tough journeyman Sumaila Badu in just the first round of a four-round contest.
[5] In 2010 Quigg defeated journeyman Nikita Lukin in Stoke on 19 February and then went on to meet Andrey Kostin in his home town of Bury on 29 May.
[6][7] Quigg's homecoming didn't last too long as he triumphed with a stoppage over his Russian opponent in just one round and in front of 1200 fans saying after the fight that "this was one of the best days of my life".
The fight at the Bolton Arena resulted in a 9th round stoppage win for Quigg against a man who had previously gone the distance in a challenge for the Scottish national title.
[9] On 25 September 2010 Quigg returned to the Castle Leisure Centre in Bury to compete for the WBA Inter-Continental title against Argentinian boxer Santiago Allione stopping him in the third round.
His opponent, the experienced Frenchman Daniel Kodjo Sassou had won the IBF International title in his last fight against Arsen Martirosyan.
Quigg defeated Venezuela's Franklin Varela via a 7th round stoppage in his second defence on 23 July 2011, and was ranked fourth in the WBA.
[11] On 22 October 2011 Quigg defeated Jason Booth (36–7, 15 KOs) to win the British Super-Bantamweight title at the Castle Leisure Centre in Bury.
[12] On 4 February 2012, Quigg made the first defence of his title, beating the rugged veteran Jamie Arthur (18–5, 4 KOs) in an eighth-round stoppage, despite being put on the canvas in the fourth.
With the fight having to be stopped, it went to the scorecards resulting in a Technical Draw with neither man getting a win or a loss on their record, bringing a very big domestic clash to an extremely anticlimactic ending.
Quigg fought at the Bolton Arena on 29 June 2013 against Brazilian Willian Prado (21–3–1, 14 KOs) at Featherweight in a scheduled 10 round bout.
It was announced on 17 July that Quigg would fight undefeated Cuban Yoandris Salinas (20–0–1, 13 KOs) for the WBA (Regular) super-bantamweight title.
[20] Quigg returned to the Phones 4U Arena on 19 April 2014 to defend his world title against South African Tshifhiwa Munyai (24–2–1, 12 KOs).
[23] Quigg made his fifth title defence against Hidenori Othake (22–1, 9 KOs) at the sold out Echo Arena in Liverpool on the undercard of Cleverly v Bellew II on 22 November 2014 live on Sky Sports Box Office.
This would only be the second time in boxing history that a Japanese boxer has come to England to challenge for the World title, the first was Mitsunori Seki, who was stopped in nine rounds by Howard Winstone in 1968 for the vacant WBC featherweight crown.
[26] It was announced that Quigg would be making a sixth defence of his WBA Regular title by taking on experienced Spaniard Kiko Martinez (32–5, 24 KOs) on 18 July at the Manchester Arena.
[27] Quigg struggled in the first round but floored Martinez in the second with a fierce uppercut and followed up with a further barrage until referee Terry O'Connor intervened, retaining his world title in the process.
It was believed that Frampton aligning with boxing manager and advisor Al Haymon may have helped get the deal across the line, due to the close relationship between him and Quigg's promoter Eddie Hearn.
[31][32] On 2 November, the fight was officially announced to take place at the Phones4U Arena in Manchester on 27 February 2016, billed for the IBF and WBA super-bantamweight titles, on Sky Sports Box-Office.
[37][38] On the other hand, the WBA Championships Committee announced Rigondeaux as 'champion in recess', due to his managerial and promotional issues and not having a fight scheduled.
His trainer Joe Gallagher confirmed Quigg would return to the ring on 10 December 2016 on the undercard of Anthony Joshua vs. Éric Molina.
He confirmed he would be travelling to the United States to train with hall of famer Freddie Roach at the Wild Card gym in Los Angeles.
[61][62][63] Quigg against 35-year-old Romanian boxer Viorel Simion (21–1, 9 KOs) was the first bout added to the undercard of the mega fight between Klitschko vs. Joshua at Wembley Stadium in London on 29 April 2017.
[65] Roach claimed that Quigg 'works harder than Pacquiao', stating, "His work ethic is great and we've seen a lot of really good changes already in the gym."
Eddie Hearn confirmed Quigg would fight on the under-card in a WBA world title eliminator against 36-year-old Ukrainian contender Oleg Yefimovych (29–2–1, 16 KOs).
[72][73] On 3 January 2018, ESPN first reported that a deal was close to being reached for Óscar Valdez (23–0, 19 KOs) to defend his WBO featherweight title against Quigg.
[83] On 20 August, Matchroom announced that Quigg would once again fight in the United States, this time at the TD Garden in Boston, Massachusetts, on 20 October 2018 on the Billy Joe Saunders vs. Demetrius Andrade card.
[86][87] On 26 February 2019, Matchroom Boxing announced the rematch between Srisaket Sor Rungvisai vs. Juan Francisco Estrada to take place at The Forum in Los Angeles on 26 April, to be broadcast live on Sky Sports in the UK and DAZN in the USA.
[90] On 26 September 2019, Eddie Hearn revealed a possible line-up for the undercard of Andy Ruiz Jr vs. Anthony Joshua rematch, which was scheduled to take place at Diriyah in Saudi Arabia on 7 December.