She went on to have small roles in both television and film including Ally McBeal, ER, Frasier, The Guardian and The Division.

Tomorrow is Today features Taylor-Compton as Julie Peterson, a girl who saves the life of and befriends a hapless drifter.

In 2007, Taylor-Compton appeared in the film An American Crime which told the true story of suburban housewife Gertrude Baniszewski, who had kept a teenage girl locked in the basement of her Indianapolis home in 1965.

Taylor-Compton then returned to the horror genre as Laurie Strode in Rob Zombie's remake of the classic Halloween.

However, in an interview conducted in July 2007, Taylor-Compton did report that after completing April Fool's Day she wanted to stay away from roles in the horror genre for her next film projects.

In 2010, she appeared in The Runaways, where she played Lita Ford, alongside Kristen Stewart, Dakota Fanning and Stella Maeve.

On April 2, 2024, it was announced by Deadline Hollywood that Taylor-Compton's directorial debut Bring the Law had wrapped production, with its script written by Josh Ridgway from a story treatment by Daniel Figueirido.

[13] The film is produced by Daemon Hillin and Carolina Brasil, and its cast includes Mickey Rourke, Peter Facinelli, Nicky Wheelan, Brendan Fehr, Leah Pipes, and Taylor-Compton's Halloween co-star Danielle Harris.

She has cited Cyndi Lauper, Gwen Stefani, Madonna, Kelly Osbourne and Green Day as her musical influences.

[18] On October 31, 2021, Taylor-Compton and Danielle Harris launched a podcast called Talk Scary to Me, in which they discuss the horror industry alongside their personal lives.

[21] In 2022, she appeared in metalcore band Ice Nine Kills' music video for their song "The Shower Scene", based on the 1960 film Psycho.

In 2023, she voiced Julie Crawford in the Texas Chain Saw Massacre video game, as well as performing motion capture for all female victims.

As a teenager, Taylor-Compton dated Andy Biersack from Black Veil Brides, who composed the song "The Mortician's Daughter" about her.