The founders of San Giovanni were a confraternity of flagellants who took part in religious ceremonies, whipping their backs and spraying blood onto the pavements as they processed through the city.
[5] A reliquary was constructed to house the relic and this was soon after connected with a miracle that reportedly took place in Venice during the period 1370-82.
According to contemporary accounts, when accidentally dropped into a canal during a congested procession the relic did not sink but hovered over the water, evading those trying to save it.
[8] This miracle was later depicted by Vittorio Carpaccio, Gentile Bellini and other artists in a series of paintings commissioned for the scuola.
In 1485 the architect Pietro Lombardo completed the school's most distinctive architectural feature, the outdoor atrium and gateway which separate the complex from the campo to which it adjoins.
Shortly after, in 1498, the architect Mauro Codussi completed work on a double staircase linking the upper and lower halls.
It is illuminated by a mullioned window on the landing between the two flights of stairs, an element common to much of Codussi's work.
[11] The school is defined externally by the open air atrium or courtyard, separated from the city by a marble screen of (1478–81) by Pietro Lombardo.
Lombardo's Renaissance screen comprises Corinthian pillars, a semi-circular pediment with St John's eagle and a frieze carved with foliage.
Though many paintings have been moved to other locations the school still houses some original artwork including Domenico Tintoretto's The Crucifixion, signed and dated 1626.