The commission included a total of nine large canvasses, by prominent artists of the time such as Bellini, Perugino, Vittore Carpaccio, Giovanni Mansueti, Lazzaro Bastiani and Benedetto Rusconi.

The item had been donated to the brotherhood by Philippe de Mézières (or Filippo Maser), chancellor of the Kingdom of Cyprus and Jerusalem in 1369, and soon became the object of veneration in the city.

The relic fell in the water: it subsequently escaped all the attempts of people to catch it, aside from that of Andrea Vendramin, the Gran Guardiano ("Grand Guardian") of the school.

The painting shows a meticulous depiction of the canale and the bridge near which the reported miracle occurred, and of a number of people who assist to it.

Some people have dived and a woman, on the right, is pushing her moorish slave to do the same: however, Andrea Vendramin has already grabbed the relic and is carrying it to the shore.