Seacroft Hospital is based in York Road in the area of Seacroft, Leeds, LS14 West Yorkshire, England and is operated by the Leeds Teaching Hospitals NHS Trust.

A decision was made in 1893 to establish a facility to care for people with infectious diseases.

A tented hospital was created at the Seacroft Estate, which had been the location of the former Manston Hall.

[6] Many of the buildings were in a poor state of repair and the health authority considered selling off the older parts of the hospital for redevelopment in 2008.

[7] The hospital was noted in 2009 for its unique and positive use of the Nintendo video game Wii Fit to assist patients with prosthetic limb in learning how to use them effectively.