He became known as the singer of the Belgian pop punk group Nailpin from 2001 until 2009 and as a video jockey on channels TMF and JIM.

Sean Dhondt started his career as musician in 2003 as a drummer of Belgian punk band Nailpin.

The single "They Don't Know" (first recorded by Kirsty MacColl in 1979 and later, in 1983, a hit for Tracey Ullman), released in 2007, peaked at number 6 in the Belgian Ultratop 50.

[7] He later became a VJ at JIM, where he presented a daily afternoon program alongside Eline De Munck.

[10] Later that year, he became the permanent co-presenter of An Lemmens on VTM during the live shows of The Voice van Vlaanderen, a role he also retained in the 2013 and 2014 editions.

In the spring of 2017, Dhondt and Rik van de Westelaken presented the seventh season of Peking Express on Q2.