To protect these lakes and the surrounding landscape, Sebezhsky National Park was established in the southwest of the district.

[8] Sebezh was first mentioned in 1414 as a fortress protecting Pskov from the south, which was later conquered by Polish troops.

The area was situated on the border between Russia and the Grand Duchy of Lithuania, changing hands several times.

In 1773, Sebezh was chartered and became the seat of Sebezhsky Uyezd in Polotsk Province of Pskov Governorate.

On August 1, 1927, the uyezds were abolished, and Sebezhsky District was established with Sebezh as its administrative centre.

[12] On August 1, 1927, Idritsky District was also established with the administrative centre in the settlement of Idritsa, including parts of the former Sebezhsky Uyezd.

A permit issued by the local Federal Security Service department is required to enter the zone.

[13] In the district, there are enterprises in the electrotechnical (capacitor production), construction, timber, textile, and food industries.

[14] The primary agricultural specialisations in the district are cattle breeding for meat and milk production, as well as potato and vegetable cultivation.

[14] The M9 Highway, which connects Moscow and Riga, crosses the district from east to west, passing through Sebezh.

The railway connecting Moscow and Riga also traverses the district, with Sebezh serving as the main station.