To date, "Second Chance" is the second-to-last hard rock song to make the top 10 of the US Billboard Hot 100.

The song has been used in promotion for the second season of Terminator: The Sarah Connor Chronicles and the 2008 WWE Tribute to the Troops show.

In May 2009, "Second Chance" was used in a promo regarding the return of character Michael Corinthos on ABC's daytime drama General Hospital.

"Second Chance", along with Taylor Swift's "Love Story", was one of two number one songs played by Casey Kasem on the last weekend of his radio career.

[citation needed] At Pointfest 22, lead singer Brent Smith told the audience;[3] "It's important for you to hear this...

It starts with a teenage girl sitting on a bench at night, and lead singer Brent Smith in the background.

It was shot at various locations on the Island, including Periwinkle Plaza in Anna Maria, the Silver Surf resort in Bradenton Beach and the Star Fish Company in Cortez.

The video stars a couple of local people; the girl is played by Alanna Massey, of nearby Parrish, Florida, and the little brother is William Bernet who lives across the street from Corky and Brenda Parker's house whose home is featured as the girl's home in the video.

On June 20, 2009, "Second Chance" reached number one on the Hot Adult Top 40 Tracks chart, almost nine months after its original release.

Overall, "Second Chance" is Shinedown's third of sixteen singles to top the Hot Mainstream Rock Tracks chart to date, having spent 10 weeks at number one beginning December 27, 2008.

In addition to chart success, "Second Chance" has been certified Platinum by the RIAA – Shinedown's first single to achieve any certification.