The series stars Daniel Hugh Kelly as Noah Beckett, whose wife Jesse (Betsy Brantley) is a veterinarian at Busch Gardens in Florida.

Noah is a former basketball coach who is now a writer working on a second book, to be titled The Ark, after his first effort has sold over 2,000,000 copies.

After Peeper's death, he is forever immortalized by taxidermy and sits proudly in front of the owner's fireplace.

Starting with the first non-pilot episode of the show, Roxanna and Luis are played by different actors, Erika Page and Jeffrey Licon respectively.

Ranny and Danny, played by Jon and Jeremy Torgerson, are twins a little younger than Ricky and Roxanna.

Later in the series, a man is introduced whom Bethany believes to be her father, though the show remains ambiguous on the truth of that claim.

There is a romance between Roxanna and Shirley's son in four episodes, "The Big Hurt"; "Faith Hope and Charity"; "Slings and Arrows"; and "The Choice".

According to various conversations throughout episodes, the order of the children's adoption is as follows: In episode 9, "The Big Chief", when Jesse explained to her father why she and Noah had no biological children, she mentioned how, when on a romantic getaway in New Orleans they saw "a newspaper article about two twins whose mother had abandoned them", which means that both Ranny and Danny were the first to be adopted.

In episode 7, "Ghost Story", Noah and Jesse reminisce on how they adopted Bethany at "two and a half years old", when they saw her "singing for her supper on the corner of Brighten and Broadway" in Tampa.

In episode 2, "Hoops and Dreams", Jesse took care of a monkey named "Caesar" after his mother, "Chloe" had died.

This pregnancy was a major change in the series, because the basic premise for why Jesse and Noah adopted so many children was because of her infertility.

Bethany was worried that she would become an outcast because of her skin color, asking Jesse during a private moment, "It's gonna look like you, isn't it?".

After the show was picked up for season one the location was moved to another Floridian style home on a lake on N. Boulevard in North Tampa where it remained until the series demise.

The last three episodes of the series aired in the summer of 1997 were re-written and re-set instead to feature, and be set at, Walt Disney World.