To fit with the James Bond theme, Clank has an array of helpful gadgets and devices on his tuxedo, such as a bow tie that he can use as a boomerang and a rose that turns into a carnivorous plant to devour enemies.

Featured are quick time events where the player must press a sequence of buttons correctly to sneak through an area undetected.

Clank has six weapons in his inventory: the Tie-a-Rang, Cuff Link Bombs, Tanglevine Carnation, Blowtorch Briefcase, Thunderstorm Umbrella, and Holo-Knuckles.

Clank secretly puts the weapons in cakes, then sends them to prison for Ratchet to pick up.

[8] A precious gem known as the Eye of Infinity, held at the Boltaire Museum, has been stolen, with Ratchet falsely accused and jailed as he is at the scene of the crime.

Meanwhile, in jail, Ratchet is forced to fend off the majority of the inmates whom he is responsible for their imprisonment to stay alive.

Although he admits he took the Eye of Infinity, he actually gave the gem to a fellow villain, Countess Ivana Lottabolts.

[12] Meanwhile, Clank heads to Lottabolts' snowy domain, Glaciara, and asks her for the Eye, but in the process is challenged to a dance of death.

Concurrently, Qwark arrives in Rionosis to continue his autobiography where he defeats the Jack of All Trades.

Back in jail, Ratchet reencourters Slim Cognito (a shady weapon tradesman met in Going Commando).

Once he is successful, Clank gets the password and is challenged to a game of poker in exchange for the box goods he saw earlier in the Casino.

With the help of the scientist, Clank escapes on a speedboat to Fort Sprocket, the real location of the Eye of Infinity.

Clank ventures into the Graveyard and the kingpin finally reveals himself – it is Klunk (his doppelganger created by Dr. Nefarious from Up Your Arsenal).

The game ends with Ratchet and Clank back in their Megapolis apartment using a vacuum cleaner which resembles Klunk.

It is an emulated version that allows for enhanced graphics, save states, rewinding, custom controls and trophies.