[4][5][6][7][8] Bill Maris' background is in technology and neuroscience, and he retired from Google Ventures (later GV) after he declared "mission accomplished.

[5][2][12][10] In December 2017, Michael Pellini, the former CEO and standing Chairman of Foundation Medicine joined S32 as a Managing Partner.

He served as both founding CEO and Executive Chairman of Thrive Earlier Detection, and President and Chief Operating Officer at Foundation Medicine.

The fund was more than double the size of its previous fund[22][23] and invested in several companies, including quantum and AI application company, SandboxAQ, which spun out of Google in 2022, and synthetic data startup, Gretel Labs.

[24] In 2023, S32 raised a $525M Fund 5 to invest in software-driven businesses in tech and healthcare that improve the human condition and named Andy Harrison as CEO of the firm.