The Seip House is a historic building on the west side of Chillicothe, Ohio, United States.

Born in Germany in the late 1810s, Charles Seip was a butcher who settled in the United States in 1845.

Soon after crossing the Atlantic, Seip took up residence in Chillicothe; he soon began operating a butcher shop on Allen Avenue, married, and became prosperous.

[2] By the 1890s, Seip's son John had persuaded his father to erect a large house on the site of his original butcher shop.

His house was one of the most prominent Queen Anne homes in Chillicothe, and he owned seven different farms in the region.