[6] Kepu captained the Wesley College first XV from the number eight position in 2004 before switching to the front row with the New Zealand under-19s in 2005.

[5] Between 2005 and 2007, Kepu was a member of the wider training group for the Chiefs, and was a standout player for Counties Manukau in the Air New Zealand Cup in 2006.

He made his Super Rugby debut on 1 March 2008 against the Highlanders in Dunedin, playing as the starting loosehead after Wallabies prop Al Baxter was ruled out due to a head knock.

[9] In the 2011 Tri Nations Series, Kepu became the first choice loosehead prop for the Wallabies after Benn Robinson was ruled out of the entire campaign due to a knee injury.

Kepu was a key player for Australia at the 2011 Rugby World Cup, starting in six of the seven matches that the Wallabies played.

[10] Kepu's re-signing led to him starting in all three knockout rounds of the 2015 Rugby World Cup, but he was ill-disciplined in the final against New Zealand, on 31 October 2015, which Australia lost 17–34.

[12] Kepu is currently playing for Counties Manukau in the 2021 NPC, and will captain Moana Pasifika for the 2022 Super Rugby Pacific Competition.