At present, it is located at the seaside village of Çevlik[1] near the town of Samandağ in the Hatay Province of Turkey.

300 BC by Seleucus I Nicator, one of the successors of the Macedonian conqueror Alexander the Great and the founder of the Seleucid Empire.

[3] The Macedonians called the landscape Pieria, after a district in their homeland that was also between the sea and a mountain range (the Olympus).

[3] When Seleucus I was murdered on his way to Macedon in 281 BC, his son, Antiochus I, buried his ashes in a building called "Nikatoreion", situated on Seleucia.

While it never recovered as a port-city again, Al-Walid ibn Abd al-Malik, Umayyad Caliph from 705 to 715, built a fortress in the city.

This means that Paul passed through Seleucia at least three times, and probably several more on pre-missionary visits to Antioch of Syria (see Acts 11:26; 12:25).

Other known bishops include Eusebius, an Arian, and Bizus in the fourth century, with twelve others cited by Le Quien (Oriens Christianus, II, 777–780).

The last-known Syriac Orthodox bishop of Seleucia, Ahron (847/874 CE), is mentioned in the lists of Michael the Syrian.

[7] The city is still a titular see of the Roman Catholic Church, Seleuciensis Pierius; the seat is vacant following the death of the last bishop in 1980.

Famous residents include Apollophanes, a physician of Antiochus III the Great (third century), and Firmus who aroused Palmyra and Egypt against Rome in 272 CE.