Self-Portrait is an oil-on-canvas painting by the French artist Simon Vouet, painted c. 1626–1627 during his stay in Rome as a protégé of Pope Urban VIII and cardinal del Monte, before Louis XIII recalled him to France in 1627.

It may have been produced as a marriage gift to his new wife Virginia Vezzi, whom Vouet married in 1626, the same year as he began the self-portrait.

It is now in the Musée des Beaux-Arts de Lyon.

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