Self-Surgery is the debut studio album by American two-piece rock band Mrs. Piss, consisting of Chelsea Wolfe and Jess Gowrie.

[2] The album's two singles, "Downer Surrounded by Uppers" and "Knelt", were released on May 14, 2020.

[3] To create an alternative version cover, Caroline Vitelli used an image from the movie The Lost Door (2008).

Mark Deming of Allmusic said "This is a bold, brave effort from two artists willing to push the boundaries of their music, and Mrs. Piss is a side project that has more than earned its reason to exist.

reviewed "Self-Surgery is heavy and punishing, darker than a lot of the music the two make on their own, and that's saying something.