Sells Brothers Circus was a circus founded by Ephraim, William, Lewis and Peter Sells in Columbus, Ohio, United States.

The circus, more formally known as the Sells Brothers' Quadruple Alliance, Museum, Menagerie, Caravan and Circus, ran from 1862 to 1863 and again from 1871 to 1895.

The circus was based out of Columbus, Ohio in an area that was known as Sellsville in Clinton Township along the Olentangy River near King Avenue.

[1] Sellsville was of considerable size, and many animals and staff lived in the area during the off seasons.

The 1901 silent film Day at the Circus by Edison Manufacturing Company features a parade and horse race from the circus.