Semerovo (Hungarian: Komáromszemere) is a village and municipality in the Nové Zámky District in the Nitra Region of south-west Slovakia.

The municipality lies at an altitude of 150 metres and covers an area of 23.409 km2.

The population is about 96% Slovak and 3% Hungarian, with other small ethnic minorities, mainly gypsy.

There was once a sizable Jewish population consisting of several families; all of them were deported to concentration camps during the years of World War II.

The village has a small public library a gym and a football pitch, and a Roman Catholic church whose base stone dates from the 9th century.