The train operated on a "two night out" schedule, departing Chicago at 9:00 PM and arriving in Jacksonville at 7:05 AM on the second morning out.

[3] The African-American dramatist and playwright T. Montgomery Gregory, then a professor at Howard University, rode the Seminole Limited in Georgia in 1915 as part of his investigation into "Jim Crow" (segregated) cars on Southern trains.

Gregory noted that even though the segregated cars on the Central of Georgia were "superior" to other railroads and that the Seminole Limited in particular was "one of the most favorable trains in the South", the train's conductor forced him from his coach at three in the morning to make room for whites who wanted to smoke.

[5] On July 1, 1967, the ACL became part of a merger product, the Seaboard Coast Line Railroad; and, thus, the SCL was a partner for the train in its final two years.

[6] On June 3, 1969, the Illinois Central truncated the Seminole from Jacksonville to Carbondale and renamed it the Shawnee.

[8] For the final Albany, Georgia to Jacksonville leg of the trip, the train[9] ran in tandem, with the matching departure times for the itinerary of the Louisville & Nashville's Flamingo.