Senai Airport Highway or Jalan Lapangan Terbang Senai, Federal Route 16 is a major highway in Kulai District, Johor, Malaysia that connects Senai International Airport to Senai, which from there connected to Johor Bahru via Federal Route 1 Skudai Highway.

[1] The Kilometre Zero of the Senai Airport Highway is located at Senai, Johor, at its interchange with the Skudai Highway (Federal Route 1), the main trunk road of the central of Peninsular Malaysia.

The highway was constructed in 1970.

In 1973, the highway was opened to traffic while the Senai Airport began operations, as well.

At most sections, the Federal Route 16 was built under the JKR U5 road standard, with a speed limit of 70 km/h.