The ancient Egyptian noble Sennefer was "Mayor of the City" (i.e. Thebes) and "Overseer of the Granaries and Fields, Gardens and Cattle of Amun" during the reign of Amenhotep II of the Eighteenth Dynasty of Egypt.

[3] He was the son of the second priest Hor-wer in Qus, Nu; his mother was a woman called Henutiry, Tiiry.

Sennefer is called son of the sister of Ahmose Humay, a male royal nurse, cousin to Amenhotep II's vizier Amenemipet called Pairy,[4] and married to the royal nurse Sentnay.

[5] His elder daughter Muttuy apparently married Kenamun, who succeeded Sennefer as mayor of Thebes.

Some containers of Sennefer and Sentnay were also discovered in KV32, the tomb of Queen Tiaa, wife of Amenhotep II and mother of Thutmose IV.