[13] He first worked in an oil mart, then in a private wine shop as a waiter and then ended up in drama where he started developing his skills.

[14] He made his debut with Oru Koyil Iru Dheepangal (1979) though officially his first film was Ithikkara Pakki, which was released in 1980.

[17][5] In 2019, Senthil has started acting in Tamil tele-serials making his debut with Sun TV's Rasathi.

[19][20] Former minister Gokula Indira was replaced in the post of organising secretary by Senthil, appointed by T. T. V. Dhinakaran in AIADMK in 2017.

In September 2019, Senthil, Kathirkamu, Raja Manickam, Devadas and Henry Thomas were announced as the five organisation secretaries of AMMK party.