He performed in the lead character Saravanan in STAR Vijay's sensational serial Saravannan Meenatchi and made his debut as a film actor in Thavamai Thavamirundhu.

He continued acting in lead roles in Sengathu Bhoomiyilae, Kan Pesum Vaarthaigal, Vennila Veedu and more.

[4] He married his co-star of Madurai & Saravanan Meenatchi Tamil serials fame Malayalam-Tamil actress Sreeja Chandran on 2 July 2014 in a private function in Tirupathi.

[5] Senthil confirmed his marriage with Sreeja on his radio show Neenga Naan Raja Sir on 8 July 2014.

[10] Senthil played the lead character in the successful television serial titled Madurai[11] in STAR Vijay telecasted from 2007 to 2009.

He continued to act in lead roles in films like Kan Pesum Vaarthaigal, Pappali, Vennila Veedu, Rombha Nallavan Da Nee, etc.