Sera Gamble is an American television writer and producer, best known for her work on Lifetime/Netflix's You, the Syfy's The Magicians and The CW's Supernatural.

[1] Before turning to film and television, Gamble starred in stage productions of Will Strip for Food in Los Angeles and Dublin, Ireland.

At the end of the fifth season, creator Eric Kripke stepped down as head writer of the series and Gamble was chosen as his successor.

While working together on Aquarius, she and John McNamara co-created and executive produced the television adaptation of Lev Grossman's New York Times bestselling novel The Magicians for the Syfy network.

[20] While working together on Aquarius, Gamble, John McNamara and Alexandra Cunningham formed the production company, Fabrication.

[21] Gamble and Greg Berlanti co-created and executive produce the television adaptation of Caroline Kepnes's bestselling novel You.

[36] In January 2021, it was announced that Gamble and Berlanti would reunite to develop a television series based on the novel Providence by Kepnes for Peacock.