Serbia competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021.

Every participant at the Paralympics has their disability grouped into one of five disability categories; amputation, the condition may be congenital or sustained through injury or illness; cerebral palsy; wheelchair athletes, there is often overlap between this and other categories; visual impairment, including blindness; Les autres, any physical disability that does not fall strictly under one of the other categories, for example dwarfism or multiple sclerosis.

[1][2] Each Paralympic sport then has its own classifications, dependent upon the specific physical demands of competition.

All of them successfully break the Paralympic qualification at the 2018 WSPS World Championships which was held in Cheongju, South Korea and two others from 2019 WSPS World Championships which was held in Sydney, Australia.

Borislava Peric-Rankovic qualified from 2019 ITTF European Para Championships which was held in Helsingborg, Sweden and other four athletes via World Ranking allocation.