Slovakia competed at the 2020 Summer Paralympics in Tokyo, Japan, from 24 August to 5 September 2021.

[6] The team is composed of Samuel Andrejčík, Michaela Balcová, Tomáš Kráľ, Kristína Kudláčová, Rastislav Kurilák, Róbert Mezík and Martin Strehársky.

[4] Slovakia sent one male and one female cyclist after successfully getting a slot in the 2018 UCI Nations Ranking Allocation quota for the European.

[10] One Slovakian swimmer has successfully entered the paralympic slot after breaking the MQS.

Marek Gergely qualified under the bipartite commission invitation allocation quota.