Serena is a freeware horror adventure game developed by several video game development companies, including Senscape, CBE Software, Infamous Quests, Digital Media Workshop and Guys from Andromeda.

The main characters are voiced by Josh Mandel and Sarah Wilson (YouTube blogger PushingUpRoses), as well as a cameo from Guys from Andromeda's Scott Murphy.

[4] The game tells a story of a man (voiced by Josh Mandel) who is waiting in a cabin for his wife, Serena, but cannot remember anything about her.

As he explores more of the cabin and examines the varying items throughout, his memories about her and their relationship begin returning, evoking multiple changes in his emotion.

[5][3][6] The title character is named after Serena Nelson, an advocate of adventure games funded by Kickstarter.