In 1960 he founded Le Trio à Cordes Français with violinist Gérard Jarry and cellist Michel Tournus.
Collot served as Professor of Viola for twenty years (1969–1989) at the Conservatoire de Paris.
Many contemporary violists have been his students: Pierre-Henri Xuereb, Jean Sulem (who succeeded him at the Conservatoire in 1989), Émile Cantor, Jacques Borsarello, Laurent Verney, Jean-Paul Minali Bella.
He has performed and lectured internationally and has served on juries of music competitions including those in Geneva and Munich.
[1] His life was the subject of a 2002 documentary film entitled L'ouvrage de Serge Collot and directed by Dominique Pernoo.