Sergei Zhigalko (Belarusian: Сяргей Жыгалка, Syarheĭ Zhyhalka; born March 28, 1989) is a Belarusian chess player who holds the FIDE title of Grandmaster.

Zhigalko competed in the FIDE World Cup in 2007, 2011, 2015 and 2017.

In 2009, Zhigalko came second on tiebreaks in the World Junior Chess Championship to Maxime Vachier-Lagrave.

In the same year Zhigalko won the European Blitz Chess Championship in Katowice, Poland.

In the European Club Cup, he won the team bronze medal in 2010 playing for Ukrainian team A DAN DZO & PGMB of Chernigiv[7] and an individual gold medal in 2013 playing board 3 for PGMB Rostov-on-Don.