In 1930-1936 Sergi Jikia worked as an assistant professor at the Leningrad University, where he was awarded with the honorary title.
[citation needed] In 1959, Sergi Jikia was invited by the Polish Academy of Sciences and the University of Warsaw to Poland with academician Giorgi Tsereteli to give lectures.
From 1960 until his death, he was a head of the department of turkology at the Institute of Oriental Studies at the Academy of Sciences of the Georgian SSR.
[6] He published Defter-i Mufassal-i Vilayet-i Georgia, dated 1595, with the original text, Georgian translation, analysis and explanations as The Great Book of the Tbilisi Vilayet.
Jikia prepared Georgian-Turkish dictionaries Azerbaijan compiling Georgian textbooks for schools in Turkey.
Sergi Jikia was awarded the medal for valiant labour in the great patriotic war 1941-1945 and the degree of a candidate of philological sciences in 1946.