His teachers were the artists Roberto Pizano, Domingo Moreno Otero, Pedro A. Quijano, Francisco Antonio Cano, Gustavo Arcila Uribe and Coriolano Leudo.

Toi et moi, is his second book manuscript with illustrations in watercolors and texts in ink and gold, with marked influence from art deco movement.

The cover of Cantique de cantiques du roi Suleiman (Song of Songs of Solomon) was made in tin embossed with inlaid ceramic, and the pages made them, just like those in Toi et moi by his own hand by calligraphic transcription of the texts, "decorating and illuminating the capital letters with details using the aesthetics characteristics of medieval manuscripts but with his own stroke of a modern painter.

"[1] In the First Annual Hall Colombian Artists wins the silver medal with the works Pastora, Anunciación y Composición (Death and the Maiden).

This became evident since he started illustrating the main newspapers and magazines in Colombia, and books, from children's stories to history textbooks and poetry.

For his literary and artistic training, said the writer Germán Arciniegas, Trujillo departed from the Spanish tradition and later tended to follow French illustrators.

And it is because his work is too varied to limit it to very precise objectives and canons, and as is nationalistic in his oils and watercolors of savanna and coastal landscapes or its many illustrations of the country's history, and as it has sought to reach the people through several murals and countless drawings published in books, magazines and newspapers, also abounds in family portraits, ideals (or long remembered) figures; religious affairs and scenes of world history, particularly in his murals and illustrations."

His versatility allowed him to capture landscapes and cityscapes that were either oil or watercolor, and make family and friends portraits in charcoal, pencil and ink.