Serhiy Yuriyovych Symonenko (Ukrainian: Сергій Юрійович Симоненко, romanized: Serhii Yuriiovych Symonenko; born 12 June 1981) is a Ukrainian retired football defender.

Symonenko started his career in Russia with Torpedo Moscow and then Alania Vladikavkaz before joining Chornomorets Odesa in 2002.

After making over 100 appearances in all competitions for Chornomorets he joined Arsenal Kyiv for the start of the 2007–08 season.

Symonenko made his debut for Ukraine on 18 February 2004 in an away draw with Libya (1:1).

This biographical article related to a Ukrainian association football defender born in the 1980s is a stub.