Serra de Tabatinga Environmental Protection Area (Portuguese: Área de Proteção Ambiental da Serra de Tabatinga) is a protected area in the states of Tocantins and Maranhão, Brazil.

The Serra de Tabatinga Environmental Protection Area in the Cerrado biome, which covers 35,185 hectares (86,940 acres), was created on 6 June 1990.

It is administered by the Chico Mendes Institute for Biodiversity Conservation.

The purpose is to protect biological diversity, control human occupation and ensure the sustainable use of natural resources.

[2] Specifically, the unit was created to protect the headwaters of the Parnaíba River to ensure water quality.