Serramazzoni (Serramazzonese: La Sèra) is a comune (municipality) in the Province of Modena in the Italian region Emilia-Romagna, located about 45 kilometres (28 mi) west of Bologna and about 30 kilometres (19 mi) southwest of Modena.

Serramazzoni borders the following municipalities: Fiorano Modenese, Maranello, Marano sul Panaro, Pavullo nel Frignano, Polinago, Prignano sulla Secchia, Sassuolo.

The first historical mention of Serramazzoni dates to 1327, when it was called Serra de Legorzano.

Serramazzoni is divided into the districts: Casa Bartolacelli-Stella, Faeto, Ligorzano, Monfestino, Montagnana, Pazzano, Pompeano, Rocca Santa Maria, Riccò, San Dalmazio, Selva, Valle, Varana.

This article on a location in Emilia–Romagna is a stub.