Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.

[1][2] Setastine acts as a highly selective H1 receptor antagonist.

[3] It has no anticholinergic, antiadrenergic, or antiserotonergic effects.

Setastine penetrates the blood-brain-barrier poorly so it is only mildly sedating compared to related molecules like diphenhydramine.

[3] This drug article relating to the respiratory system is a stub.