Setting apart is a ritual or priesthood action in the Church of Jesus Christ of Latter-day Saints where a person is formally blessed to carry out a specific calling or responsibility in the church.
Once a person has accepted the responsibility of holding a church calling and has been accepted by the members for that position, one or more Melchizedek priesthood holders "set apart" the person to serve in that calling.
If the recipient is being set apart as a president of a priesthood quorum, including a stake president or a bishop, "priesthood keys" are also conferred upon them.
[1] Generally, only general authorities and local leaders of stakes, wards, missions, districts, and branches may set apart a member to serve in a position.
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