Settle Junction railway station was located near the town of Settle, North Yorkshire, England, immediately to south of the junction between the Midland Railway's North Western and Settle-Carlisle branches, 39+3⁄4 miles (64.0 km) northwest of Leeds.

It was opened five months after the main line to Carlisle to serve as an "exchange station" with the older route to Morecambe (as stated in an 1872 report submitted to the Settle and Carlisle Construction Committee of the MR by General Manager James Allport and Chief Engineer John Crossley[1]).

[2] Its remote location (1+3⁄4 miles (2.8 km) south of Settle and 2 miles (3.2 km) north of Long Preston) undoubtedly contributed to its early demise, as potential travellers had the choice of three alternative stations (Settle, Giggleswick or Long Preston) that were all more conveniently sited for their respective communities.

The box houses a London Midland Region standard frame of 31 levers and controls the busy double junction (which was rebuilt following a derailment in 1979) between the two lines, as well as the block sections toward Hellifield to the south, Blea Moor Sidings to the north and Carnforth Station Junction to the north west.

The latter is the longest block section on the UK rail network at just over 24 miles (39 km) in length and severely restricts the capacity of the Carnforth line (a typical passenger train is timetabled to take 40 minutes to travel from one end of the section to the other, including station stops).