At 20 years old, he wrote, directed and produced a micro-budget film based on his own life, titled My Big Fat Armenian Family.

Ohanian co-produced the film Fruitvale Station, written and directed by fellow USC graduate Ryan Coogler.

[4][5] In 2014, Ohanian produced a two-minute Google Glass spot called Seeds, directed by Aneesh Chaganty.

The short became an internet sensation after garnering more than one million YouTube views in 24 hours,[6] and earned him a spot on The Wrap's 2014 Innovator's List of "Thought Leaders who are Changing Hollywood.

[11][12] Searching premiered at Sundance 2018, and was theatrically released in August by Sony Screen Gems, making over $75 million worldwide.

[23] In February 2021, it was announced Ohanian's company Proximity Media has signed a five-year exclusive TV deal with Disney.