Frog anime series consists of the fifty-one episodes after episode two-hundred-and-five from the series, which first aired in Japan from April 5, 2008 to March 28, 2009 on TV Tokyo.

Season 5 uses 5 songs: 2 Openings and 3 Endings.

"Nante Suteki na Doyōbi" (なんて素敵な土曜日, "What a Wonderful Saturday") by Keroro Platoon is used as the opening from episode 206 to 231.

"Bokura no Aikotoba" (僕らの合言葉, "Our Password") by Natsumi Kiyoura is used as the ending from episode 219 to 244.

"Kekkekkeroro no Daisakusen" (ケッケッケロロの大作戦♪, Ke-Ke-Keroro's Big Plan) by the Keroro Platoon is used as the ending from episode 245 to 256.