[6] Founded in 1976 as a single campus, the university has grown in both keeping its reputation and physical enlargement whilst developing a strong and transparent system of higher education in the north of Sindh.

[1] The university is noted for its academic staff consisting of foreign scholars, and research directed towards the development of humanities, archaeology, Sindh studies, natural and social sciences.

[1] In addition, it is ranked as one of the top institution of high learning by the HEC on "general" category.

Another campus was therefore set up at Khairpur Mirs, named after the national poet of Sindh, Shah Abdul Latif Bhitai.

In 1986, the Sindh provincial assembly passed an act to make the campus a full-fledged and independent university.

The act came into force in 1987, making the university functional, under then-Chief Minister Ghous Ali Shah.