The opening ceremonies was held on April 24, 2012, with the first doubleheader of volleyball games at the Filoil Flying V Arena in San Juan.

[1][2] At the end of the elimination round, the Lady Eagles of the Ateneo de Manila University and the Tigresses of the University of Santo Tomas (UST) emerged on the top of standings in their respective group via complete sweep 4–0.

The UST Tigresses snagged a solo second spot after beating NU Lady Bulldogs in straight sets on the last day of quarterfinals.

On the other side, San Sebastian forced a rubber match but UST won in three straight sets on the deciding game to face Ateneo in their first Finals meeting.

Group B featured the league's winningest team, the UST, as well as Adamson, Letran, San Sebastian, and USLS.