Shamsher-ul-Hyderi was born in the Kadhan (Sindhi: ڪڍڻ) town of Badin District, Sindh.
After an early education in his native village, Shamsher-ul-Hyderi briefly attended Sindh Madressatul Islam University in Karachi before graduating with both BA and MA degrees in Sindhi from the University of Sindh in Jamshoro.
His various employers included: the Pakistan Public Works Department (as clerk), the Cooperative Bank in Badin (as manager), the Sindhi Adabi Board (as clerk, and in 1993 Secretary), Mehran magazine (as assistant editor), Naee Zindagi Monthly magazine (as editor), the National Shipping Corporation[2] (as publishing manager), Daily Mehran newspaper (as editor), and Daily Hilal Pakistan newspaper (as editor).
Shamsher-ul-Hyderi's appreciation of literature began with an introduction from his maternal uncle Nazeer Hyderi.
He was later guided by the scholars Maulana Ghulam Mohammad Grami and Muhammad Ibrahim Joyo.