Saxena started his career in the early 1970s and has mainly played supporting roles.

He has starred in some of the most successful films of Hindi cinema like Mr. India, Tridev, Ghayal, Khiladi, Ghulam, Gupt: The Hidden Truth, Duplicate, Soldier, Baghban, Fanaa, Krrish, Ek Hi Raasta (1993), Bajrangi Bhaijan and many more.

His performances in these films have established him as one of the best supporting actors in Bollywood.

He played the role of Kichaka in the television serial Mahabharat.

Sharat Saxena was born on 17 August 1950 in Satna, Madhya Pradesh.