Headquartered in Atlanta, Sharecare was founded in 2010 by Jeff Arnold (founder of WebMD) and Dr. Mehmet Oz, in partnership with Remark Media, Harpo Studios, Sony Pictures Television and Discovery Communications.

[4][5][6] Sharecare began as an interactive question-and-answer (Q&A) platform about health[7] and then expanded its products and services through internal development and strategic acquisitions of companies including DailyStrength, dotFit, The Little Blue Book, WisePatient, RealAge, PKC Corporation, BACTES Imaging Solutions, QualityHealth, Feingold Technologies, BioLucid and Healthways.

[citation needed] AskMD guides users through a personalized questionnaire that takes into account symptoms and other factors, like medications and known conditions, and matches answers against available clinical research.

In the RealAge Test, users typically fill out a questionnaire about their health history, which is then used to generate personalized content, including highly targeted advertisements.

[26] Such knowledge partners include (among others): Colgate-Palmolive; Pfizer; Unilever (Dove skin-care products); health insurer UnitedHealthcare; and Walgreens drug stores.

ADA President Dr. Robert A Faiella summed up the group's reaction by stating: "As a science-based organization, we should always welcome inquiry, but we should not be seen as supporting the promotion of misleading information unsupported by the best science.