She is best known for her roles on daytime television soap operas, scoring parts in the serials General Hospital and As the World Turns during the early stages of her career.

[8] As of May 2019, Case was in a relationship with her The Young and the Restless co-star, Mark Grossman, who plays Adam Newman, one of the character's love interests on the soap.

[2] In November 1989, Case scored her first television role playing Dawn Winthrop on the ABC Network soap opera General Hospital.

Case wanted to "perfect" her audition prior to screen testing as Dawn, who served as the long-lost daughter of the long-running character Monica Quartermaine (Leslie Charleson).

Speaking of the audition, Case stated: "I practiced night and day [...] It was a heavy scene in which Dawn learned that her boyfriend Ned (Kurt Robin McKinney) had once slept with her mother!

[11] She departed General Hospital the next year, after a guest appearance on another ABC series, the comedy drama Doogie Howser, M.D..

In 1991, Case appeared in various other television series, including Diplomatic Immunity, Beverly Hills, 90210, Parker Lewis Can't Lose and Cheers.

[6][12] From November 1992[13] to 1993 Case stepped into her second soap opera role, as Debbie Simon on the CBS Network drama As the World Turns.

Case has stated that she loved the role, and wanted to stay on to explore more into the character of Debbie who was a "manic depressive", an issue that hadn't been covered on daytime television.

In 1994, a year after departing from As the World Turns, she became a regular on the primetime soap opera Valley of the Dolls, which was based on the romantic novel of the same name.

[18] In 2009, Case appeared on an episode of the sex comedy web series Poor Paul which was created by former The Young and the Restless co-star Kevin Schmidt.

In June 2010, Case starred opposite David James Elliott in the romantic comedy Dad's Home for the Hallmark Channel.

[30] The show's cast and viewers were appalled when Sharon was romantically paired with her former father-in-law who she had grown to have a father-daughter relationship with, Victor Newman (Eric Braeden).

20 different designs of jewelry pieces were featured in the line's initial reveal through the shopping cable QVC Network in August 2010; prices ranged from $20–40.

noted that "they are touted to be ideal for a night on the town, giving 'The Young and the Restless' fans an affordable way to sparkle and shine with star-quality by wearing star-designed jewelry".