The Amboy Dukes performed in a "senior class only" concert, in the football stadium, May, 1971.

Another program unique to Shawnee Mission South was that of the Center for International Studies.

The Center for International Studies (CIS) provided intensive instruction in four languages: Arabic, Chinese, Japanese, and Russian.

The program also provided students the opportunity to attend geopolitics classes rather than regular social studies courses.

[12] In 2005, South's Science Olympiad team made district news by winning the state of Kansas competition and advancing to the national level.

Throughout its history, Shawnee Mission South has won several state championships in various sports.